Showing posts with label Progesterone. Show all posts
Showing posts with label Progesterone. Show all posts

Friday, September 20, 2013

PCOS Awareness Month

Hi All!

In case you didn't know, September is PCOS awareness month! Please pop on over to http://www.pcosfoundation.org to learn more about PCOS or, Polycystic Ovarian Syndrome.

There are many different types of infertility – but PCOS is among the top causes. It's not only relatively common but it also has many faces. The disease, it's symptoms and the prognosis all vary per individual woman.

Some women achieve success with ovulation inducing medications like Clomid or Metformin – while some have to use IVF, and others never achieve pregnancy at all. This makes it challenging to treat because there is no scenario or case study to follow. We're all so different, and our experiences with PCOS are all so different, that it's difficult to come up with a single prognosis.

The other thing about PCOS is that it is not just an infertility disease. It's lifelong. PCOS lasts long after you're no longer trying to have children, and some women experience it well into menopause. It's a condition that can affect your health for the rest of your life if not treated and maintained properly. That's, perhaps, the cruelty of it for women who never succeeded in having children – the constant reminder of their infertility until their childbearing years are well over.

Sometimes it can be really difficult to get a diagnosis – because there's no typical PCOS situation and each doctor seems to have their own idea of what makes a PCOS diagnosis. Some doctors believe insulin resistency is a requirement of PCOS, while others say it's only a disease of the overweight. However, I can assure you that neither of those have to be present for you to have PCOS. Due to this inconsistency in knowledge, it can be difficult to get diagnosed and a get on an effective treatment plan. My advice to you is that if you suspect you have it, but your doctor disagrees - get a second (or third) opinion. Look online for a PCOS specialist in your area and make an appointment. PCOS creates different fertility obstacles and being treated properly, for the right condition, could be the jump start your body needs.

A PCOS diagnosis does not mean the end of your journey, but it certainly changes it. Many women go on and have healthy, normal pregnancies – but for some, the journey to the pregnancy is a little rockier. Other women chose different paths – whether it be adoption, surrogacy, or living child free. The importance of understanding, and spreading awareness, about PCOS is so that more women can ask their doctors the right questions, and ensure they get the best possible care during their fertility journey.

 ** I am not a professional, nor do I have an professional experience with PCOS. My experience is purely personal, and based on research. Please visit the above link for more information, or speak to your doctor. 

Wednesday, September 4, 2013

A backstory on Amy!

Hello and Welcome to Ask an Infertile!

I was thrilled when Melissa, my dear awesome friend, announced that she was starting this blog. I was even more thrilled when she said she was looking for contributers! My struggle with infertility was actually not with conceiving but with carrying babies past the first trimester( and even then...but that will be discussed further down!)...so here it is, a long biography on me and my struggle to actually have in my arms my two fantastic children. Please note though that I am a Canadian( our health systems are not the same) and that I speak French( our language is not the sa...wait, that is just an evidence. What I meant with that was that probably some sentences might be weirdly constructed or words might be mispelled. I do my very best and do have an education! I swear!!)

I am 26 years old. I was pregnant six times and have two living children. six pregnancies in six years of being frisky between the sheets. I am a mean machine...or not. I got pregnant for the first time I was 18 years old. Young, immature...definitely not ready for motherhood. I decided to terminate that pregnancy after a lot of fighting with my boyfriend at the time, who was not ready either. I was 12 and a half weeks along.

I got on birth control pills for a little while,then we decided we actually wanted to try for a baby. Neither of us had grieved the loss of our child correctly and we naively thought that a new pregnancy would put a balm on our wound. I got pregnant again a year and a half after the loss. I was then 19.  Oh joy, I thought as I saw the second line appear on that stick. I was pregnant again! Then I started panicking. I was starting a new job two days later! I went on working and kept my pregnancy a secret, wanting to at least finish training before announcing I would leave to birth a child. Two weeks into the six weeks training, I started spotting. Bright, red and horrifying blood. The spotting only intensified, followed by cramps. That night, at home, I passed a cloth that was tissue. I was about 7 or 8 weeks along. My first miscarriage. I was...devastated. I had killed my first baby, now the universe and karma were taking my second child!

It took me a while before getting pregnant again. We were not trying, not preventing. And then BAM, in June 2009 there it was: a bright, beautiful and dark positive on a first response. I cried, then laughed. I was pregnant for a third time! I couldn't help but be scared out of my mind for this baby to stick...and he did! In february 2010 I gave birth to my son, my perfect little boy. Finally I had a baby, the baby I had been wanting for close to three years. I was ecstatic, in love...and had mad baby fever. seven months after his birth, I was back in the TTC game, determined to have an other baby soon so my son would have a sibling close to his age. HA...right.

You see...TTCing is a bitch. Because you want it badly...and nothing. Month after month after month you are disapointed. Month after month you grieve that pregnancy that never happenned. Month after month...it hurts. And boy it was long before I finally did conceive. My big boy was almost two. It was in September 2011 that I got a positive again...and after four days I started bleeding.Chemical pregnancy.I was having a rough time in my relationship at that point. My son's father and I decided at that point to stop trying to conceive and work on our relationship.I was checking my cervix to identify the days I was fertile in the month and was able to pin point my ovulation fairly easily and identify the days I was fertile. Worked great to avoid a pregnancy...for a few months. I am allergic to latex( yay...) and one of my fertile days...well we had le sex. I warned my then boyfriend that I was fertile. He did not care. and two weeks later( december first 2011)...tada! I was pregnant for the fifth time!...and ten days later, I became a single mother.

Let's just say that 2012 started sourly for me. 25 and moving back in with my parents with my near 2 years old son and with an other one on the way. I debated a long time with myself, unsure if I should interrupt the pregnancy or keep my baby. I also started a relationship with my now husband, who was a dear friend of mine waiting patiently.( Patient, patient man!) I finally decided I was keeping the baby and confronted my ex about it because he didn't wanted me to go trough with the pregnancy. We went together to my first prenatal appointment. We couldn't hear a heartbeat so I was sent for an ultrasound. I was 11 weeks along.

On the ultrasound, we saw a perfectly fine and alive baby wiggling around in my stomach. I joked that it was a girl because it was dancing and prancing around. I was pregnant, my baby was alive and healthy, I was in a new relationship with the perfect man for me...my life was starting to take a turn for the better.

Or so I thought.

three weeks later, at exactly 14 weeks 1 day I woke up with insane pressure. I thought I needed to pee so started to walk towards the bathroom. I did not reach it. I got soaked on the doorstep. Thinking I peed myself, I cleaned up real quick and went back to bed. An hour later, I woke up again with regular contractions. It wasn't pee...it was my water that had broken. I will spare you the details of what happenned next, for your sake and mine. To this day, this loss still hurts. It was a little boy. I named him Augustin.

After losing my son, I went on a rollercoaster of emotions, really. At my check up, the high risk doctor thought my uterus looked funny and sent a request for a MRI. I went trough an emergency D&C because I had some leftover placenta that was undetected at the follow up that got majorly infected. And I waited...and waited...and waited for the call abck for the MRI. I finally got the test in June. In July, I got my results. Everything was normal! OH JOY!...still my loss was unexplained. The doctor prescribed me progesterone pills that needed to be taken as soon as I would get a positive, to help with my placenta in case that was where the problem was. In spetember, I finally got an other positive and started the intra vaginal pills. Now a year later, I am sitting here with a gorgeous and fussy little girl on my lap. My journey trough baby making is over. My husband and I decided that we were done after having our little ray of sunshine, my rainbow baby.

So...that was/is my story with TTC and losses. It is a bit confused and clearly amateur haha...I am just a  beginner when it comes to this blogging thing...;)



Tuesday, August 27, 2013

Unexplained Infertility

Labels.  They are everywhere.  As much as we try not to, we are always using them.  During my struggle with infertility, I "gained" this label.

Unexplained infertility, meaning that if there was a reason I wasn't getting pregnant, they couldn't identify it.  This is a label you get if all the tests that are run produce normal results.  My husband's sperm analysis was normal, as were my blood tests for insulin resistance and my baseline ultrasound. My estrogen, prolactin, FSH (follicle stimulating hormone), and TSH (thyroid stimulating hormone) levels were all fine.  It appeared that I ovulated on my own, based on my progesterone levels late in my cycle.  And yet, I wasn't getting pregnant.

I found that not having a reason, not having something to blame, was frustrating.  If you don't know what you're up against, it can be difficult to fight it.  At first, my RE (reproductive endocrinologist) thought that a round or two of Clomid would do the trick.  It would give my body a little boost, maybe help timing a bit.  When that didn't work, he suggested an HSG test. (Click here for a definition)  The test showed no major abnormalities, although my left fallopian tube did not fill with dye.  My RE was sure that this was because I have experiencing some pretty substantial cramping during the test (look for a post describing my HSG experience soon).  I trusted him, and we carried on, bolstered by the knowledge that many woman have a higher chance of conceiving shortly after the test is done, usually because small blockages and debris could be flushed out by the test.  Around this same time, I told one of my nurses that I was having spotting leading up to my period, around 11 or 12 days after ovulation. Dr. B decided to having me take progesterone supplements during my leutal phase.  Progesterone is a hormone produced by the body, the level of which rises after ovulation.  If a woman becomes pregnant, the corpus leuteum cyst, which is left behind after the follicle releases the egg, is maintained by the HCG (the pregnancy hormone) in the blood, so it continues to release progesterone.  If the body doesn't start producing HCG, the progesterone level falls and the lining of the uterus is shed.

Dr. B theorized that perhaps I was a late implanter, meaning for one reason or another, an egg takes a little longer to travel to the uterus to implant.  If it took longer than 11 or 12 days, it was possible that my uterine lining was already beginning to shed before a fertilized egg could implant there.  By having me take supplements, my progesterone level stayed up, and I didn't start my period.  If I tested negative for pregnancy, I was to stop taking the progesterone supplements and my period would start 2 or 3 days later.

Two months later, we switched to Femara.  I responded well, ovulating earlier than even on Clomid.  My normal ovulation was sometime between day 18 and day 22.  This isn't necessarily indicative of a problem.  Most woman ovulate anywhere between CD 11 and 21.  Fertility drugs made me ovulate sooner in my cycle.  Later ovulation can sometimes point to poor egg quality, but not always.

After our first round of Femara, when I found out I wasn't pregnant, I went in for my usual ultrasound. While I was there, I expressed my frustration to one of the nurses.  She was very nice and suggested we do a more monitored cycle and try a trigger shot, which would better time the moment of ovulation and make it stronger.

That month, we conceived.  Did lengthening my leutal phase help me get pregnant?  Did ovulating sooner in my cycle help me conceive? Was it just chance? We can't be sure.  Since we didn't know what, if anything, was behind me inability to get pregnant, we will probably never know, unless a problem arises.  It's possible we could go on and have more children easily.  But we could also experience the same problems.

The point to this post is this:  Fertility issues like PCOS, endometriosis, and low ovarian reserve are fairly well known and if the correct tests are done or if symptoms are noted, the are usually quickly identified and treated.  Less obvious issues (whether there is a known medical reason or not) can also lead to years of infertility.  Maybe a lot of woman labelled with unexplained infertility have a medical issue that just can't be identified yet.  Science has come a long way, but we are constantly hearing of new developments, tests, and treatments, perhaps someday there won't be so many people with this label.  I certainly hope so.  And I applaud doctors, like my own, that try to treat the problem, even if they can't really identify it.  I don't think I'd have my second son if not for them.

Friday, August 23, 2013

Welcome to Ask An Infertile!

Welcome to Ask An Infertile!  I'm Melissa, and I created this blog because in my opinion there can never be enough resources and outlets on the subject of infertility, TTC, and pregnancy loss.  I am hoping that this blog will because a place to get information about all forms of infertility.  So many woman have questions, and what do we do in the 21st Century when we have questions?  We Google it, of course!  I know I do.  So again, why this blog?  Well, to answer that, I think I'd better start off by telling you a little more about me.

Today, I'm a 31 year old working mom to two incredible little boys, living in Indiana with my wonderful husband of 9 years and the worlds greatest grandma, my mom.  In 2010, when my first son, Tyler, was 18 months old, my husband and I decided we were going to try for our second child, since we wanted our children to be fairly close in age.  When we had started TTC Tyler, we became pregnant about 8 months after I stopped taking birth control pills, so while I didn't expect us to succeed immediately, I didn't think it would take a terribly long time.  Six months or so, that was my guess, factoring in that fact that I hadn't been using any hormonal birth control since we'd had Tyler.

At the suggestion of my doctor, I started tracking my cycles carefully.  I kept notes on my calendar and purchased a fancy little app on my smartphone.  At that time, my cycles were a little irregular, though not alarmingly so.  Sometimes it was 28 days long, but it could go as long as 37 days.  One thing that became clear pretty quickly was that I wasn't sure when I ovulated.  Over the next few months I tried various methods of predicting ovulation.  I charted my BBT (basal body temperature).  I checked my cervical position (I was terrible at that).  I monitored my cervical mucus (ew).  I eventually turned to using OPKs (ovulation predictor kits).  For awhile, even these stumped me!  The first brand I tried would turn positive and then stay that way for 5 or 6 days! 

When I had been trying for about 7 months, I turned to the internet for advice and support.  I found an online forum and I was suddenly thrust into the world of infertility and TTC on the internet.  I was amazed that not only did others feel like I did, but A LOT of others did!  I started making some incredible friends and following their stories.  Suddenly TMI didn't exist!  We talked about our bodily fluids, we talked about BDing with our SOs and DHs (that's baby dancing with our significant others and darling husbands).  We took pictures of our peesticks and scrutinized them together, fiddling around in photo editors to try to see if that might be a line?  We shared the disappointment of another BFN (big fat negative), gave each other advice, and on good days, shared in the excitement of a friends BFP (big fat positive).  We offered sympathy and encouragement.  Suddenly I wasn't alone in this strong desire to have a child.  And that felt nice.

As nice as it was to have support, I was still getting frustrated.  In April 2011, I visited my primary care "doctor", A, who is actually a Physician's Assistant.  I'd been seeing her for many years and just absolutely ADORED her.  She was her usual awesome self, listening to my frustration, letting me let those few tears fall.  She even shared with me a little of her own struggle for children.  She sent me on my way, asking me to try one more month of charting my BBT (I'd given up on it a few months prior), and telling me to come back for a referral to a specialist if I wasn't pregnant in May.

Just my luck, during that crucial week in May I was sick as a dog with a fever.  Dutiful little patient that I was, I trudged into June, knowing I needed real data to bring back with me.  On June 17th, I posted a picture of my negative pregnancy test, saying I just wanted to get my period over with and go back to see my doctor.  Then a member of the forum said she thought she could see a faint line.  Then another agreed.  And another.

I should interrupt myself here with a note--I have TERRIBLE eyesight.  I've worn glasses since I was a toddler.

Anyway, I hadn't seen anything on the test, but that really didn't mean much.  A few girls edited my photo and yes, maybe that was the start of a line?  Only time would tell.

The next morning, I dutifully POAS (peed on a stick).  And there was a faint, but visible second pink line.  It was the day before Father's Day, May 18th, 2011.  It had taken just over a year, but I was pregnant!

But then, so soon after that exciting moment, I wasn't anymore.  I spotted a little bit on Sunday, but my HPT was darker, which comforted me.  Then I spotted a little more on Monday.  On Tuesday, four days after my first true positive HPT, I took another test and the second line was barely detectable.  I went to the doctor and had a blood test, then went home, put my feet up, and fought from assuming the worst.

Unfortunately, the next morning my worst fear was realized.  My hcg level was already down to the point where they considered the result to be negative.  The nurse actually told me I'd never been pregnant at all.  I was completely devastated.  I sat down and cried.  I drove to work, crying.  I worked, alternating between tearing up every time anyone said hi to me, to trying my damnedest to think of ANYTHING else.  I ended up telling more people that I'd miscarried than had known I was pregnant in the first place.  I felt totally cheated.  And more than that, I felt an incredible amount of depression at the though that I'd gotten so close and now I had to start over.

Logically, I knew that this pregnancy had ended so early, there wasn't truly much more than a fertilized egg, some divided cells.  But in my heart, that was the potential baby I wanted so much.  That was another Tyler.  Maybe a brother.  Maybe a girl this time, a little sister.  But that was ripped away, almost before I could even celebrate it.

I mourned my loss.   I went back to see A, even armed with pictures of my positive tests.  She assured me that, of course I was actually pregnant, but that the egg probably implanted later than usual and so my HCG level never got terribly high before it began to drop.  She said that these kind of miscarriages are called "chemical pregnancies" and they are actually pretty common.  An egg with chromosomal problems, or one that doesn't implant correctly will simply be expelled by the body, which senses that something isn't right.  She said that often women don't even know they were pregnant with these.  But she also recognized that to me, to any woman trying to have a baby, it was a loss, and it was okay, natural even, to be sad about it.

She gave me a referral to a specialist, a reproductive endocrinologist (RE).  As a matter of fact, the same RE that had helped her get pregnant with her little girl.  I called him and made an appointment for the next month.

The cycle after my miscarriage was painfully slow and, well, painful.  I had heavy bleeding and terribly cramps, but it only last about 6-7 days.  I was still using OPKs and instead of a positive result somewhere between CD 18 and CD 22, it was CD 28 before I got a positive result.  I had heard that a miscarriage, even an early one, can mess up a woman's cycle.  Yay.

On July 20th, my husband and I went to see my RE, Dr. B.  I liked him immediately.  He was very understanding and listened carefully, asking thoughtful questions.  He said based on my history, I probably just needed a little "boost" to get pregnant again.   And I learned that since I had one child, I was experiencing what is called "Secondary Infertility" meaning I hadn't had trouble conceiving my first child.  I would later learn that my infertility is also considered "Unexplained Infertility" since a cause for me not conceiving easily was never discovered exactly, although there were a few minor things that I think contributed to it (shorter than average leutal phase, indications of late implantation, low progesterone).  He also told me that although there would be times that I would be disappointed, to try not to be discouraged, because together we'd get through it.

First order of business when seeing an RE is a whole mess of tests.  My husband submitted to a sperm analysis, which came back fine.  I had a glucose tolerance test, and ultrasound, and several blood tests.  Everything came back normal, so Dr. B prescribed me a pill called Clomid.  Clomid is a fertility drug that can cause ovulation in someone who isn't ovulating regularly or can encourage a healthier ovulation in someone like me, who is ovulating, but not at the best time of the cycle (Later ovulation can cause the quality of the egg to be lower). During that time, I was also put on progesterone supplements during my leutal phase, since it was on the shorter side and my RE thought I might be getting my period before an egg had the chance to implant. I eventually did four cycles on Clomid.  While I ovulated on day 15 or 16 each month, we did not get pregnant.  Eventually, I had a test called a Hysterosalpingogram or an HSG.  This is an X-ray test where dye is injected into the uterus so that they can see if there are any abnormalities in the uterus or fallopian tubes.  My result was normal, aside from my left fallopian tube not filling.  My RE attributed that to the cramping I experienced during the test. 

During our final cycle of Clomid, we met with Dr. B again to discuss our options.  We could try another pill, called Femara (Letrizole), which is similar to Clomid, but some people respond better to.  Or we could switch to injection hormones, which are more effective, but carry a higher chance of multiples and, usually, a higher price tag.  After checking with my insurance (which covers some fertility treatments and test, but not all), we decided we would start with Femara and save up money to try injections in a few months.

Month one of Femara passed with Christmas 2011 and a BFN.  In January, we decided to do a more monitored cycle.  Basically that meant that I would return to Dr. B's office for a second ultrasound (I had one every month around CD 3 to check for cysts and things) a few days before I expected to ovulate.  At this appointment, they would check the lining of my uterus to make sure it looked thick and healthy, but not too thick and they would check my ovaries for follicles.  They would also have me inject a medication to trigger a stronger ovulation, called an HCG trigger shot.  This basically mimics the surge of LH (ovulation hormone) in the body, causing all mature follicles to release their eggs.  On CD 13 my ultrasound showed good lining and two follicles that showed promise.  The next evening, I injected $85 worth of medication into my muffin top (LOL) and hoped for the best.  Oh, and a fun side effect of this shot?  Since it contains the pregnancy hormone, you get a positive result on an HPT!  I just had to try that out!  I watched the lines fade, but I wasn't sure they had totally vanished.  Finally, with doctor's orders to test 14 days after my injection, I was excited and terrified to see two pink lines!  I rushed to the doctor for a blood test and was told that my HCG was 12.7.  And I was told that was "probably pregnant".  Luckily, I was able to return with confidence two days later for another test, encouraged by darkening lines on HPTs.

So that's my story.  It took 19 months, an early miscarriage, four rounds of clomid, an HCG two rounds of femara, a trigger shot, many progesterone pills, countless ultrasounds and a lot of home pregnancy tests on OPKs, but I was pregnant.  I was truly blessed to give birth to my second son, AJ, in October 2012.

So.  Yes that was a pretty long story.  Anyway, if you're still with me (please stay with me!), that brings us back to the present.  My sons are 4 1/2 and 10 months, but I still reflect on my journey and how it changed me.  I was "lucky", really.  I've read so many blogs, heard so many stories that was much more arduous than my own.  So many people are still struggling, have experienced grief and pain so far beyond what I had felt.  And even as time passes, I still feel very drawn to this community.

During my personal struggle, I wrote on my personal blogger blog, but I also contributed to a blog on a popular website called Countdown to Pregnancy.  I told my story, the same story as is written above, but with more detail.  And when I finally became pregnant, I stepped away.  But every once in awhile, I still get a notification that I have a new comment.  I got one today.  It was from a girl looking for advice.  I responded and then I started thinking.  I LIKED this.  I was kind of GOOD at this.  I may not have had the most harrowing story to share, but it was one that was related to and I really enjoyed sharing what I knew.

And so, Ask an Infertile was born.  So to speak.

I don't pretend that this is a new idea.  But as I stated way up there at the top of this very long post, there really can't be ENOUGH resources out there.  So here we go.